RET Fusion mutation drugs – lung cancer

Activated RET and ROS: two new driver mutations in lung adenocarcinoma http://tlcr.amegroups.com/article/view/1031/1683   RET Inhibitors Vandetanib In April 2011 the FDA approved vandetanib, a RET, VEGF 2, VEGF 3 and EGF receptor tyrosine kinase inhibitor for the treatment of patients with metastatic MTC who were ineligible for surgery and had progressive or symptomatic disease. The […]

Anti-aging combo on Amazon

Amazon links. N (R) Niagen Nicotinamide Riboside https://www.amazon.com/Niagen-Nicotinamide-Riboside-60-capsules/dp/B00L5Q951S/ref=sr_1_2_s_it?s=hpc&ie=UTF8&qid=1474577659&sr=1-2&keywords=niagen Pterostilbene Longevity and Antioxidant Supplement https://www.amazon.com/Pterostilbene-Resveratrol-Longevity-Antioxidant-Supplement/dp/B00JQS5T76/ref=sr_1_2_s_it?s=hpc&ie=UTF8&qid=1474577726&sr=1-2&keywords=Pterostilbene Pterostilbene inhibits lung cancer through induction of apoptosis. http://www.ncbi.nlm.nih.gov/pubmed/20031166   NAD+ and SIRT1: Their Role In Chronic Health Issues

Cancer Notes

Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375728/ Inhibitors of RET, a tyrosine kinase receptor encoded by a gene that is frequently mutated in medullary thyroid cancer, have emerged as promising novel therapies for the disease. Rapalogs and other mammalian target of rapamycin (mTOR) inhibitors are effective agents in patients with […]

Snowden should be pardoned

Letter to the Editor Whistle blower Edward Snowden who revealed information about the illegal Bush/Obama NSA spying program is a national hero and should be pardoned. Yes – what he did was illegal. But if he didn’t act that too would have been illegal. The NSA had been lying to Congress about what it was […]

Putin like Trump because he’s weak and stupid

Letter to the Editor I find it somewhat amusing that presidential candidate Donald Trump thinks that Russian president Putin likes him is a good thing. Putin is a power hungry dictator who wants to restore the former Soviet Union to power, and the best think that could happen for Putin is to have an incompetent […]

I have bad news. I have stage 4 lung cancer

I have some very bad news. For the last 25 years I have been one of the nations most prolific letter to the editor writers. Unfortunately that might come to and end soon as I have been diagnosed stage 4 lung cancer. As someone who understand probabilities far too well I understand this is a […]

Insurance Companies Aetna and Humana should not be allowed to merge

Letter to the Editor In a move to intimidate the Justice Department insurance giant Aetna threatened to pull out of Obamacare if government regulators interfered with its merger with Humana. The health insurance merger should not be allowed to continue. The reason that the government regulates the super corporation is to prevent one company from […]

John McCain does not deserve reelection

Letter to the Editor Senator John McCain, a former prisoner of war in Vietnam, has endorsed Donald Trump in spite of the fact that Trump has advocated the use of torture on prisoners. Trump has also disparaged prisoners of war like McCain calling him and all POWs losers because they were captured. And Trump jokes […]

Wow! Do I ever miss Bill Clinton

Letter to the Editor After seeing Bill Clinton speak tonight I no longer care if Hillary is lying about whatever. I want Bill Clinton back in the White House!

I was expecting Trump to grow up

Letter to the Editor I watched Trump’s acceptance speech at the convention and his behavior since and he’s is acting like a brat. I’m talking about this ongoing feud between Trump and Cruz. In the primary it was amusing. It was refreshing to get some unfiltered opinions, no matter how weird they may be. But […]

Clinton picks Big Bank Advocate for VP

Letter to the Editor It is very unfortunate that Hillary Clinton picked a VP running mate who is advocating for the deregulation of banks just 8 years after deregulation caused a economic collapse and added some 10 trillion dollars to the national debt. While the big banks got bailed out, the American people got royally […]

Republicans have already lost the Presidential Election

Letter to the Editor The Republican Party is slowly grasping the reality that they have already lost the presidential election. I’m not saying that Trump isn’t going to win. I’m saying that Trump is not, never was, and never will be a Republican. The Republican voters chose a non-Republican over 16 other Republicans. And I […]

Why can’t Americans see the last 28 pages?

Letter to the Editor After America was attacked on 9/11 there was an investigation and a report was issued. However the last 28 pages of the 9/11 report remain secret, classified by the Bush administration. Apparently the 28 pages are not something that Saudi Arabia wants released and they have threatened to sell off some […]

Are we really having a primary election?

Letter to the Editor I used to think America was a Democracy where the People elected the politicians and our votes counted. But that doesn’t seem to be the case in this year’s election. This year the Democrats and Republicans have rigged their primaries. And that’s neither Democratic, nor the American Way. In a Democracy […]

Denying Supreme Court Numinee a Hearing

Letter to the Editor There is a Constitutional question I’ve been wondering about. The President shall have the power to justices of the Supreme Court “by and with the Advice and Consent of the Senate”. But what happens if the Senate refuses to participate in the process as they are doing now with Judge Garland. […]

I’m tired of Billionaires controlling the election

Letter to the Editor America has had terrible presidents for the last 16 years. First we had Bush who crashed the economy and got us into wars in the middle east. Then we had Obama who passed out trillions of dollars to the super rich and let the bankers get away with it. No bankers […]

Trump being honest about Abortion

Letter to the Editor People on the left and right are criticizing Trump for saying the if you make abortion illegal that women who get abortions would go to jail. After all, that is what the word illegal means. When people oppose abortion they don’t think things through. That’s why we need to keep abortion […]

Violence at Trump Rallies is Trumps Fault

Letter to the Editor Donald Trump started this and what happened Friday in Chicago was Donald Trump’s fault. Trump started it by encourage violence at his political rallies. Trump said about a protester “I’d like to punch him in the face, I’ll tell you that,” and offered to pay the legal expenses of those who […]

Money does Influence Politics

Letter to the Editor Like Secretary Clinton, President Obama took Wall Street money and look at what happened. None of the bankers who ripped us all off went to jail. In the 1980s President Reagan sent 700 bankers to jail. So I have to agree with Senator Sanders that money corrupts. Under Sanders there will […]

Hillary’s Email Problem

Letter to the Editor A lot of people are arguing about Hillary Clinton’s email problem. Is it a big deal or is it a big deal over nothing? But I think people are missing the real point here. The government goes to a lot of trouble to make sure that the Secretary of State has […]

Difference between Clinton and Sanders is …

Letter to the Editor I think there’s really one defining difference between Hillary Clinton and Bernie Sanders in this presidential race. Bernie’s message is “Yes we Can” and Hillary’s message is “No we Can’t” on issues like single payer heath care and free college tuition. It reminds me of the 2012 election when Bill Clinton […]

Does Obama want Trump to be the Republican Candidate?

Letter to the Editor President Obama did a press conference today where he said, “I continue to believe Mr. Trump will not be president”. I believe he’s sincere about that but it makes me wonder if Obama realizes that he has effectively endorsed Trump for Republican nominee. If you’re Republican and you don’t know who […]

Republicans challenge the President of Scalia

Letter to the Editor Now that there is an opening on the Supreme Court the Republicans are saying that they will refuse to process and appointments that President Obama will make. That they will refuse to allow Obama to make the choice even though he is still president. It makes me wonder if they would […]

People are tired of Republicans and Democrats

Letter to the Editor Donald Trump and Bernie Sanders have something in common. Donald Trump isn’t a real Republican and Bernie Sanders isn’t a real Democrat, and that’s why I think they are so popular right now. People are tired of Republicans and Democrats. First we had 8 years of Bush who collapsed the economy. […]

Clinton Email Very Disturbing

Letter to the Editor People are wondering if Hillary Clinton’s email scandal is something to worry about and the short answer is – yes it is. She was the Secretary of State and in that role she had access to top secret information that only the top people in government knew. For example – when […]

SpaceX makes history!

Letter to the Editor I want to congratulate Elon Musk and SpaceX for making history today by landing the first stage of a rocket back on Earth (in one piece this time) after deploying a payload into space. This is an historic event because the cost of getting stuff into space just got at least […]

Ben Carson not a threat to “progressive secular movement”

Letter to the Editor Ben Carson says that the reason that people are looking into his past is that he’s a threat to the “progressive secular movement”. I think he’s more of a threat to religion than he is to us heathen atheists. Religious people are supposed to be inspired by God to tell the […]

Candidates should be asked about NSA Spying

Letter to the Editor Whether you are a tree hugging liberal or from the Ku Klux Klan conservative one thing we all have in common is that we don’t like the government spying on us. Now we are in the debate season to determine who is going to be president and those who question the […]

Jailing Clerk over Gay Marriage is right thing to do

Letter to the Editor I think the jailing of Kim Davis, the Kentucky Clerk who refused to issue marriage licenses to same sex couples was the right thing for the judge to do. Like many older Americans I think gay marriage is “a little weird”. But this is America where people have the freedom to […]

Pope moves in right direction on Abortion

Letter to the Editor I find myself again praising Pope Francis, His latest change on abortion is a step in the right direction. As a non-catholic I didn’t know abortion was an unforgivable sin and that it was just upgraded to forgivable. I personally don’t think abortion is a sin at all. In fact – […]